Israeli leaders on Tuesday were debating how best to respond to Iran’s unprecedented weekend airstrike, officials said, weighing a set of options calibrated to achieve different strategic outcomes: deterring a similar attack in the future, placating their American allies and avoiding all-out war.

Iran’s attack on Israel, an immense barrage that included hundreds of ballistic missiles and exploding drones, changed the unspoken rules in the archrivals’ long-running shadow war. In that conflict, major airstrikes from one country’s territory directly against the other had been avoided.