10 people were killed, and 15 were injured in a series of stabbings in an Indigenous settlement and a neighboring town in the Canadian province of Saskatchewan, police said Sunday as they looked for two suspects.

Multiple stabbings occurred in the James Smith Cree Nation and the community of Weldon, northeast of Saskatoon, according to police.

RCMP Saskatchewan Assistant Commissioner Rhonda Blackmore stated that some of the victims appear to have been targeted by the suspects, while others seem to have been attacked randomly. She was unable to identify a motive.

"Today's events in our province are horrifying," Blackmore stated.

She stated that thirteen crime sites contain either deceased or injured victims. She encouraged the suspects to surrender.

Blackmore stated that police began getting reports of stabbings in the First Nation community before 6 a.m. Police issued a warning at noon that a vehicle containing the two suspects had been observed in Regina.

The suspects were last seen in Regina, Saskatchewan's capital, at about lunchtime, according to the police. There have been no subsequent sightings.

"If you are in the Regina region, take precautions and consider seeking shelter in place." Never leave a safe spot. NOT TO APPROACH strange individuals. Avoid picking up hitchhikers. Call 9-1-1 to report suspicious persons, crises, or information. The RCMP tweeted: "Do not disclose police locations."

Doreen Lees, an 89-year-old grandmother from Weldon, and her daughter believed they saw one of the suspects as a car sped down their neighborhood as her daughter drank coffee on the terrace early in the morning. According to Lees, a man approached them and stated he was hurt and needed assistance.

But Lees said the man fled after her daughter stated she would phone for assistance.

"He refused to reveal his face. A large jacket covered his face. "When we asked him his name, he mumbled it twice and we still couldn't get it," she claimed. He stated that his face was so severely wounded that he could not reveal it.

She stated that the man was alone and "kind of shaky."

"I followed him a short distance to ensure his safety. My daughter told me, "Don't follow him; return here."

Diane Shier, a resident of Weldon, was in her garden on Sunday morning when she spotted emergency personnel a few blocks away.

Shier said that her neighbor had died. She wished to conceal the victim's identity out of respect for his family.

She said, "I am very upset because I lost a good neighbor."

The search for suspects was conducted as people arrived in Regina for a sold-out, annual Labour Day game between the Saskatchewan Roughriders and Winnipeg Blue Bombers of the Canadian Football League.

The Regina Police Service stated in a press release that, with the assistance of the Mounties, it was working on many fronts to locate and apprehend the individuals and had "deployed additional resources for public safety throughout the city, including the football game at Mosaic Stadium."

As the two suspects remained at large, the RCMP in Melfort, Saskatchewan, increased the notice to include Manitoba and Alberta several hours later.

Damien Sanderson, age 31, was reported as five feet seven inches tall and weighing 155 pounds, while Myles Sanderson, age 30, was six feet one inch tall and weighing 200 pounds. Both individuals have black hair and brown eyes and may be driving a black automobile.

According to the Saskatchewan Health Authority, multiple patients are being treated at multiple locations.

Anne Linemann, a spokesperson for the authority, said in an email, "A call for additional staff was issued to respond to the influx of casualties."

STARS Air Ambulance spokesman Mark Oddan stated that two helicopters were despatched from Saskatoon and one from Regina.

Two ambulances transported patients to the Royal University Hospital in Saskatoon, while the third transported a patient from a hospital near Weldon to Royal University.

"Today's attacks in Saskatchewan are horrifying and tragic. "My thoughts are with those who have lost a loved one and those who have been injured," tweeted Canadian Prime Minister Justin Trudeau.

"We are constantly following the situation and encourage everyone to follow local authorities' updates. Thank you to the courageous first responders for their efforts on the scene."

The James Smith Cree Nation has declared an emergency.