Nine members of one family -- including six children -- were killed in a US drone strike targeting a vehicle in a residential neighborhood of Kabul, a relative of the dead told a local journalist working with CNN.

The US carried out a defensive airstrike in Kabul, targeting a suspected ISIS-K suicide bomber who posed an "imminent" threat to the airport, US Central Command said Sunday.

The youngest killed was a 2-year-old girl, according to a brother of the one of those killed.

They were "an ordinary family," he said. "We are not ISIS or Daesh and this was a family home -- where my brothers lived with their families."

Neighbors and witnesses at the scene of the drone strike in Kabul told CNN that several people were killed, including children.

"All the neighbors tried to help and brought water to put out the fire and I saw that there were five or six people dead," a neighbor told CNN. "The father of the family and another young boy and there were two children. They were dead. They were in pieces. There were [also] two wounded."